IBD Treatment in Hyderabad | Crohn's & Colitis Specialists

By Kage Team | 16 March 2026

IBD — Inflammatory Bowel Disease: Expert Treatment in Hyderabad

Living with inflammatory bowel disease means navigating an unpredictable cycle of flares and remissions abdominal pain that arrives without warning, urgent dashes to the bathroom at work or social gatherings, fatigue that drains every reserve, and the constant anxiety of not knowing when the next attack will come.

IBD encompassing Crohn's disease and ulcerative colitis is a chronic, lifelong condition that significantly impacts quality of life and, if not treated appropriately, can lead to serious complications including bowel surgery.

At KIMS Advanced Gastroenterology & Endoscopy — KAGE, at KIMS Hospitals Secunderabad, Hyderabad, we have a dedicated IBD Clinic staffed by specialist gastroenterologists including Dr. Bhaskar Kante (Fellowship in IBD from AIIMS) and Dr. Sreekanth Appasani (20+ years of experience in interventional gastroenterology) providing the most advanced, evidence-based IBD care in Hyderabad. If you are in Secunderabad, Begumpet, Ameerpet, Himayatnagar, or anywhere across Hyderabad, expert IBD care is available right here.

What Is Inflammatory Bowel Disease (IBD)?

Ulcerative Colitis (UC): Inflammation limited to the colon (large intestine) and rectum. Ulcerative colitis causes continuous areas of inflammation and superficial ulcers in the colon lining.
Crohn's Disease: Can affect any part of the digestive tract from mouth to anus most commonly the last part of the small intestine (terminal ileum) and beginning of the colon. Crohn's causes patchy, transmural (full-thickness) inflammation and can lead to fistulas, abscesses, and strictures.

IBD is distinct from IBS (Irritable Bowel Syndrome), IBD involves actual structural inflammation and tissue damage visible on colonoscopy and biopsy, whereas IBS is a functional disorder with no visible inflammation.

Causes and Triggers of IBD

IBD is caused by an abnormal immune response in which the immune system mistakenly attacks the intestinal lining. The exact trigger is not fully understood but involves:

Genetic predisposition: IBD has a strong hereditary component — first-degree relatives of IBD patients have a significantly higher risk.
Gut microbiome dysbiosis: An imbalance in the gut's bacterial community is strongly implicated in IBD pathogenesis.
Environmental triggers: Changing dietary patterns, reduced microbial exposure, smoking (increases Crohn's risk but oddly reduces UC risk), certain medications (NSAIDs, antibiotics), and psychological stress.
Increasing incidence in urban India: IBD once considered rare in India is rising rapidly in urban populations including Hyderabad, driven by Westernization of diet, increased hygiene, antibiotic use, and changing gut microbiome patterns.

IBD Symptoms: How Crohn's and Colitis Present

Ulcerative Colitis Symptoms

Recurrent bloody diarrhea the hallmark symptom
Urgent, frequent need to pass stools often 5–10+ times per day in severe flares
Crampy lower abdominal pain, particularly before bowel movements
Feeling of incomplete evacuation (tenesmus)
Fatigue, weight loss, and anaemia during flares
Fever during severe attacks

Crohn's Disease Symptoms

If you have persistent bloody diarrhea, severe abdominal pain, or significant weight loss, do not delay — visit KAGE, KIMS Hospitals Secunderabad immediately. These symptoms require urgent specialist evaluation.

Chronic diarrhea may or may not be bloody depending on the area affected
Crampy, often severe abdominal pain particularly in the lower right abdomen
Significant weight loss and malnutrition due to malabsorption
Perianal disease fistulas, fissures, and abscesses around the anus
Mouth ulcers, skin lesions, eye inflammation, and joint pain extra-intestinal manifestations
Fever and fatigue during flares

Diagnosing IBD at KAGE's Dedicated IBD Clinic

Accurate IBD diagnosis requires a combination of clinical assessment, laboratory tests, and endoscopic evaluation with biopsy:

Colonoscopy with biopsies: The gold standard for diagnosing and assessing the extent of IBD. At KAGE, performed with Olympus X1 HD and Fuji ELUXEO colonoscopes for exceptional mucosal detail.
Upper GI Endoscopy: Required in Crohn's disease to assess involvement of the upper GI tract.
MRI Enterography: The best imaging modality for assessing small bowel Crohn's disease and perianal disease does not involve radiation.
Fecal Calprotectin: A non-invasive stool biomarker that distinguishes IBD (elevated) from IBS (normal) particularly useful for monitoring disease activity and treatment response.
CRP, ESR, and CBC: Blood tests to assess systemic inflammation, anaemia, and nutritional status.
Capsule Endoscopy: Used for suspected small bowel Crohn's when other tests are inconclusive available at KAGE.

IBD Treatment at KAGE: Comprehensive, Personalized, and Advanced

Medical Therapy Inducing and Maintaining Remission

5-ASA (Mesalazine): First-line for mild to moderate ulcerative colitis reduces inflammation and maintains remission.
Corticosteroids: For inducing remission during flares not for long-term use.
Immunomodulators (Azathioprine, 6-Mercaptopurine, Methotrexate): For maintaining remission and reducing steroid dependence.
Biologic Therapies: The most significant advance in IBD treatment in the last two decades. Anti-TNF agents (infliximab, adalimumab), anti-integrins (vedolizumab), and anti-IL-12/23 agents (ustekinumab) are used for moderate to severe IBD not responding to conventional therapy. KAGE's IBD Clinic at KIMS Hospitals Secunderabad has extensive experience in initiating and monitoring biologic therapy.
Small Molecule Therapies (JAK Inhibitors): Newer oral agents (tofacitinib, upadacitinib) for moderate-severe UC an exciting recent addition to the IBD armamentarium.

Nutritional Support

Malnutrition is common in Crohn's disease. Exclusive enteral nutrition (EEN) is used to induce remission in Crohn's particularly in children. Nutritional rehabilitation is a core part of IBD management at KAGE.

Endoscopic Treatment of IBD Complications

Endoscopic balloon dilatation for Crohn's strictures, avoiding surgery
Endoscopic drainage of perianal abscesses
Surveillance colonoscopy IBD patients have increased colorectal cancer risk and require regular endoscopic surveillance

Conclusion

Frequently Asked Questions

No, IBD and IBS are very different conditions that are frequently confused. IBD (Inflammatory Bowel Disease) involves actual inflammation, ulceration, and structural damage to the intestinal lining visible on colonoscopy and confirmed by biopsy. IBS (Irritable Bowel Syndrome) is a functional disorder characterized by abdominal pain and altered bowel habits without visible inflammation. Fecal calprotectin testing is a simple, non-invasive way to differentiate between the two available at KAGE.

Currently, there is no permanent cure for IBD it is a chronic condition. However, the goal of modern IBD management is deep remission complete resolution of symptoms and mucosal healing (confirmed by colonoscopy). With the advanced biologic and small molecule therapies available at KAGE's IBD Clinic, many patients achieve prolonged remission with excellent quality of life. The KAGE IBD team monitors each patient's treatment response closely and adjusts therapy proactively.

Biologic therapies are a class of advanced medications that target specific proteins driving intestinal inflammation in IBD including TNF-alpha, integrins, and interleukins. They are used for moderate to severe Crohn's disease and ulcerative colitis that has not responded to conventional therapies. Biologics have transformed IBD outcomes significantly reducing flare frequency, preventing bowel damage, and allowing many patients to avoid surgery. KAGE's IBD Clinic has extensive experience in initiating, monitoring, and optimizing biologic therapy.

Not all IBD patients require surgery in fact, with the advances in biologic therapy available at KAGE, many patients who would previously have needed surgery can now be managed medically. However, surgery remains necessary for complications including bowel obstruction, perforation, severe bleeding, fistulas not responding to medical therapy, and dysplasia or cancer. When surgery is needed, it is performed through close collaboration between KAGE's gastroenterologists and surgical colleagues at KIMS Hospitals.

KAGE's dedicated IBD Clinic is located at the Gastroenterology Department, KIMS Hospitals, C/O Gastroenterology Dept, KIMS Hospitals, 1-8-31/1, Minister Road, Secunderabad, Hyderabad – 500003. The IBD Clinic is staffed by Dr. Bhaskar Kante (Fellowship IBD from AIIMS) and Dr. Sreekanth Appasani two of Hyderabad's most experienced IBD specialists. Available Monday to Saturday, 9:00 AM to 5:30 PM. Call +91-7288842255 or email appointments.kage@gmail.com to book an appointment.